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Download e-book for iPad: Addiction and the Medical Complications of Drug Abuse by Steven B. Karch MD FFFLM

By Steven B. Karch MD FFFLM

Extracted from the Drug Abuse guide, second variation, to provide you simply the data you would like at an inexpensive expense. dependancy and the scientific problems of Drug Abuse explores the physiological and mental phenomenon of dependancy together with the character of dependence, the dependence power of gear, and the significance of motivation. Contributions study the perform of alternative prescribing and aspect the instant and long-term merits in their use in upkeep or managed withdrawal from opioids, stimulants, and benzodiazepines. It considers using methadone, buprenorphine, adrenergic agonists, and naltrexone for detoxing. Practitioners will enjoy the professional guideline at the administration of universal comorbidities, together with analysis and pharmaceutical remedy of mental issues. additional info covers the physiological results of every drug and the emergency administration of numerous drug similar issues similar to psychosis, seizures, stroke, hyperthermia, and cardiac drawback. With 29 tables and figures, professional facts and huge references, this is often an vital publication for a person within the box of dependancy or emergency drugs.

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Extra resources for Addiction and the Medical Complications of Drug Abuse

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This time span may be only a few weeks but can be as long as a few years in some cases. In summary, naltrexone is a competitive opioid antagonist that displaces opioid agonists from the opioid receptors and blocks the effects of opioid agonists subsequently administered. It is a useful adjunct to psychological relapse prevention methods in well-motivated individuals receiving treatment for opioid dependence. 2 STIMULANT-SPECIFIC PRESCRIBING A useful pharmacotherapy for stimulant (cocaine and amphetamine) dependence remains elusive.

1. Substitution treatment (such as methadone) has historically been confined to specialist clinicbased programs. Recent decades have seen the expansion of substitution maintenance and detoxification treatment into primary care (general practice and community pharmacy) settings in many countries in order to “normalize” addiction treatment, reduce treatment costs, and increase the accessibility of services. , where trained and accredited physicians can deliver BPN treatment outside of clinic settings (“office based prescribing”).

Subutex, Suboxone) are tablets with approximately 50% bioavailability of the ethanol solution. fm Page 19 Friday, August 31, 2007 10:03 AM SUBSTITUTE PRESCRIBING: BUPRENORPHINE MAINTENANCE PRESCRIBING 19 Objectively, there was no significant difference between the two groups on measures of opiate withdrawal symptoms. 10 A 24-h dosage interval is most commonly recommended. Opiate-dependent subjects find BPN an acceptable treatment for their dependence and report a “morphine-like” effect. 11 Due to its wide therapeutic index, BPN is relatively safe in overdose.

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